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10 An overall 15% decrease in body weight was observed with 5 mg/week dosing alongside a 19.5% decrease in body weight with 10 mg/week dosing and a 20.9% weight reduction with 15 mg/week dosing

Compound: Insulin-Like Growth Factor-1 Long Arginine 3 (IGF-1 LR3) Concentration: 100mcg per vial Format: Lyophilized Powder (Strictly for In-Vitro Laboratory Use) Chemical Classification: Recombinant Growth Factor Analog Chemical Profile: IGF-1 LR3 is a synthetic, modified version of the naturally occurring Insulin-Like Growth Factor-1

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GLP-1R expression was not detected in the HEK293T cell line before transfection (Supplementary Fig