As men and women age, aromatase activity takes place at the testosterone precursor, Androstenedione, at a higher rate than the aromatase activity at Testosterone observed in younger populations
This interaction may lead to changes in the receptor's structure, initiating a series of molecular events that may activate signal transduction pathways within the target cells
Ao neutralizar os radicais livres, molculas altamente reativas que danificam as clulas, ela preserva a integridade dos tecidos e promove a regenerao celular, acelerando assim o processo de reparo
However, evidence suggests vitamin D may exert positive effects on multiple cellular pathways affecting proliferation, apoptosis, DNA repair, and extracellular matrix signaling (Vergara 2021)