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Oral/Labial Melanotic Macule Etiology and Pathogenesis The melanotic macule is a unique, benign, pigmented lesion that has no known dermal counterpart

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Vitamin B12 Replacement Conclusion B12 deficiency is under appreciated and underdiagnosed

Statistical analysis was performed by t -test (unpaired or paired, as indicated), one-way analysis of variance (ANOVA), two-way ANOVA (time treatment or genotype treatment) with post hoc comparisons (where appropriate, as indicated in the figure legends)