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Supplementation has been linked to increased expression of slit diaphragm proteins such as nephrin and podocin, as well as reduced tubular injury, possibly through anti-inflammatory and anti-RAAS mechanisms (53)

Pozo et al., 2017)

This is likely to become a less salient issue as drug developers develop new formulations with more convenient dosing routes and schedules since overall simpler dosing (fewer steps, less frequent dosing) tends to improve medication satisfaction and adherence (Boye et al., 2021)