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Contact and combat-sport athletes (MMA fighters, BJJ practitioners, rugby players, hockey players, football) commonly use the BPC-157/TB-500 combo for the repeated soft-tissue impact pattern these sports create, paired with GHK-Cu for skin and barrier repair from mat burns, lacerations, and chronic abrasion

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Residues E542 and E545 in PIK3CA , and S45 in CTNNB1 , are recognised mutational hotspots in cancer 27