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72 DPPIV is a key enzyme that degrades GLP-1, 73 which regulates glucose-dependent insulin secretion

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GLP-1R binding sites were detected in islet and neuroendocrine tumours, as well as in a subset of brain tumours [160]

Oral Medications and Gastric Emptying Ozempic section 7.2 states that the drug delays gastric emptying and has the potential to affect absorption of concomitantly administered oral medications, that clinical pharmacology trials showed no clinically relevant effect on absorption, and that caution should nonetheless be exercised