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& Konopaske, G

En modelos animales, esa seal se asocia con formacin de nuevos vasos sanguneos y con mejores marcadores de reparacin en tejidos con irrigacin limitada como tendones y ligamentos

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[7] The protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell death and increases resistance to toxic challenges, especially oxidative stress

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