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while X-ray is unlikely to damage the protein, manufacturers haven't validated it and hand inspection is universally available

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In those situations, the margin between "acceptable zone" and "danger zone" shrinks considerably

Patients screened had type 2 diabetes were treated with basal insulin for at least 6 months, receiving a stable daily dose of between 15 and 40 units alone or combined with 1 or 2 OADs (metformin, sulfonylurea, glinide, SGLT-2 inhibitor or a DPP-4 inhibitor), had an HbA1c between 7.5% and 10% and a FPG less than or equal to 180 mg/dL or 200 mg/dL depending on their previous antidiabetic treatment