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Typically occurring between ages 45 and 55, perimenopause transition is characterized by fluctuating estrogen levels and declining ovarian function that initiate a cascade of physiological and psychological changes that extend far beyond reproductive health

We show that the increase of p-IGF1R expression in tumoral lung tissues correlated with proliferation (Ki67), macrophage (Iba1) and tumor-associated macrophage, TAMs (CD68) presence (Pearsons correlation coefficient, r = 0.5906, p = 0.0013

The limited long-term data on sustained microdosing protocols necessitates careful monitoring and regular assessment of metabolic parameters

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