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Request and review the Certificate of Analysis (COA) to confirm the use of semaglutide base API

GLP-1 receptor agonists enhance insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite

Given the benefits of tirzepatide on weight, waist circumference, and lipid parameters in addition to impressive improvements in glycaemic control, this medication appears to be ideally placed as first add-on therapy for individuals not at HbA1c target on metformin, particularly for those with T2D and excess adiposity (Table 2, clinical scenario A)

It is particularly common among older demographics, where skin becomes less effective at producing Vitamin D, or among people with darker complexions