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GLP-1 receptor agonist drugs work by mimicking the action of the GLP-1 hormone to regulate blood sugar levels

It has been shown that LF-derived peptides mechanisms of hypotensive action involve not only the inhibition of ACE but also interactions with the renin-angiotensin system, the endothelin system, and regulation of gene expression encoding proteins involved in the NO pathway and prostaglandin synthesis (61)

however, immunohistochemistry (IHC) investigations revealed decreased expression of IGF-1, 8-OHdG, and ARs in both tumor and adjacent normal tissues

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