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In addition, chitosan nanocarriers can directly deliver drugs to the lymphatic system through lymphatic targeting technology, increase local drug concentration and reduce systemic toxicity

40, 41 At one time it was thought that any solution which will not produce a slough when injected perivenously will generally not be strong enough to obliterate a vein. 42 However, some very effective sclerosing solutions are thought to act selectively on damaged varicose endothelium

Even modest weight reduction of 5-7% significantly enhances insulin receptor function in muscle and liver tissue