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An alcohol mediated increased production of pro-oxidants, as well as adecrease in the antioxidant defense systems (enzymatic and non-enzymatic) in the liver may contribute to the development of ALD

Key finding: GHK identified as top compound for reversing age-associated gene signatures

However, long-term safety data, cost-effectiveness analyses, and the refinement of patient stratification strategies remain essential considerations prior to broader clinical implementation (96, 169)

Therefore, when Mn and Pt are integrated into a bimetallic nanozyme, their complementary catalytic features may function cooperatively