This is, to our knowledge, the first description of a three-way contact between an endosomal GPCR, the ERMCS tether VAPB, and a PKA-RI-recruiting AKAP, which uncovers the assembly of a GLP-1R-induced ERMCS-localised PKA biomolecular condensate to control mitochondrial turnover and function
2 Beyond the liver, MASLD has systemic consequences, with strong associations with cardiovascular disease, chronic kidney disease, and extrahepatic metabolic complications
You likely know which days after injection are hardest, which foods sit well, and how your energy levels are shifting
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