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Animals were housed in home cages and the entire home cage was placed in a custom IH chamber (0.62 0.55 0.29 m 3 ) during IH exposure

This review comprehensively discusses the sources and mechanisms of ROS generation, the associated pathophysiology of diseases, and the role of both endogenous and exogenous antioxidants in mitigating oxidative stress

In a Phase I crossover study involving healthy volunteers (NCT04384666), the pharmacokinetic profile of a single dose of LY03003 (28 mg) injected intramuscularly was compared with a 7-day regimen of Neupro, indicating that the injectable system could provide sustained drug release over an extended period 140

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