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Together, these results support a model in which venous-derived (Aplnr + ) ECs give rise to Esm1 + cells, which, in turn, differentiate into Bmx+ arterial ECs and thereby progressively contribute to the mesenteric arterial network (Supplementary Fig

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Patients with a history of cobalt allergy may be at increased risk, as all cobalamins (including hydroxocobalamin and cyanocobalamin) contain a cobalt atom in their molecular structure