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Curcumin inhibited IL-6-induced proliferation, migration, and invasiveness of human small cell lung cancer (SCLC) cells by reducing JAK/STAT3 phosphorylation (i.e., activation) and downstream genes coding for cyclin B1, survivin, Bcl-X L , MMPs, intercellular adhesion molecule 1 (ICAM-1), and vascular endothelial growth factor (VEGF) (30)

Indeed, most treatment options for long COVID, which focus on modulating neuroinflammation, vascular defects and energy metabolism alterations due to mitochondrial dysfunction, have been inspired by treatment approaches for PAIS and ME/CFS [31]

doi: 10.1016/j.jtbi.2013.08.037