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Depletion of beneficial taxa such as Odoribacter (Bacteroidetes) and Lachno Clostridium (Firmicutes), along with increased abundance of pro-inflammatory taxa including Ileibacterium and Olsenella , was associated with reduced SCFA gene expression, downregulation of tight junction proteins (occludin and claudin-1), and microglial activation in the amygdala and arcuate nucleus, indicating gut barrier disruption and neuroinflammation that coincided with anxiety-like behavior

A family history of IBS

Senthil S, Veerappan RM, Rao MR, Pugalendi KV (2004) Oxidative stress and antioxidants in patients with cardiogenic shock complicating acute myocardial infarction

It enhances the production of collagen peptides