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10.1016/j.neuroscience.2006.11.065 Neuroscience

That said, several indirect mechanisms could potentially contribute to breathing difficulties in patients taking Ozempic: The medication's effect on gastric emptying and its association with gastrointestinal side effects may lead to bloating, abdominal distension, or gastro-oesophageal reflux, which can occasionally create a sensation of breathlessness or chest tightness