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It can be top-dressed on feed or mixed with soaked forage pellets, beet pulp, or grains

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It is the most appropriate choice for people who feel persistently tired, mentally foggy or run-down, or who follow a diet that limits B12 intake

To ask how -KG insufficiency depletes the cytosolic NADPH pool, we first confirmed that cytosolic NADPH-producing enzymes ME1 and IDH1 are essential for cell survival during energy stress, as previously reported 26,31 , because knockdown of either gene sensitized Huh7 and H1299 cells to glucose starvation (Supplementary Fig