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Xiang C, Werner BL, Christensen EM, Oliver DJ (2001) The biological functions of glutathione revisited in arabidopsis transgenic plants with altered glutathione levels

Continuous lipid accumulation impairs mitochondrial function and elevates ROS production, 64 leading to lipid peroxidation, DNA damage, and protein denaturation, collectively initiating oxidative stress, inflammatory signaling, and hepatocellular injury