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10.1016/s1089-8603(02)00124-6 105 WeidnerW.HauckE

Obesity in women from developing countries

Genetic differences within this network may affect the risk of OP by modifying the GM

Over time, mutated mtDNA molecules can undergo clonal expansion, and once the mutational burden exceeds a critical thresholdtypically 60% and 90% they produce a biochemical defect in OXPHOS, a concept referred to as the mtDNA mutational load (112)

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