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Statins are safe in patients with fatty liver disease and should be used when indicated for cardiovascular risk reduction

However, from clinical studies alone, it is difficult to know how much of the benefit is due to direct effects in the joint and how much may be explained by weight loss or broader metabolic changes. That is why we wanted to address a basic mechanistic question first: whether GLP-1 is actually present in the joint environment

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This slowing allows for a more gradual absorption of glucose into the bloodstream, which helps mitigate spikes in blood sugar levels after meals, a common challenge for individuals managing diabetes