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Ex-Vivo studies on living tissue with a minimum change of natural conditions were conducted

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(2013) Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans J Endocrinol Metab 3(12):715 AOD9604 vs Related GH-Axis Research Tools AOD9604s unique combination of GH receptor independence, direct lipolytic activity, absence of IGF-1 stimulation, and confirmed oral bioavailability makes it an irreplaceable research tool for studying adipose tissue metabolism and lipolysis without the systemic endocrine confounds associated with intact hGH or indirect GH secretagogues

In a separate analysis, the model was re-estimated using data from a trial in subjects with type 2 diabetes