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Nobili V, Vajro P, Dezsofi A, et al

Statements Data availability statement The original contributions presented in the study are included in the article/ Supplementary Material

Moreover, IGF-IR has kinase-independent functions, such as nuclear translocation and regulation of gene expression, and interaction with SGLT1 to maintain intracellular glucose levels [209]

"We're excited that these data, the first phase 3 data of a next-generation amylin therapy, show promise and we look forward to further investigating Cagrilintide's potential in the dedicated phase 3 RENEW programme," Lange added

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