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Researchers considering extended protocols should be aware that this safety gap exists and should monitor for unexpected effects in tissues where NNMT has normal physiological functions

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NNMT inhibition in diet-induced metabolic regulation models Source: PMC8337113 Summary: This research investigated 5-Amino-1MQ in diet-induced obese mice, measuring body weight, adipose tissue mass, and adipocyte size changes over an 11-day study period