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2006, 60-90 mcg/kg doses were well tolerated in men aged 20-40, and most effects are dose-dependent, typically resolving within 7-28 days of dose reduction or discontinuation

This aligns with the moderate behavioral improvements seen in social interactions, suggesting that oxidative stress and excitatory overactivity continued to drive damage despite partial restoration of GABAergic function

GSH levels were highest in maitake mushrooms, closely followed by pioppini and lions mane and popular eating mushrooms like porcini, shiitake and oyster mushrooms also had good levels of GSH

Validation experiment based on parallel reaction monitoring (PRM) To further validate our proteomics data, we selected proteins related to lipid synthesis (Cd36, Fabp2, Fabp4, Plin2, Plin4, and Plin5), fatty acid oxidation (FAO) (Cpt1a, Acaa1b, and Cyp4a10), the mitophagy-lysosome pathway (Bnip3, Sqstm1, Optn, Map1lc3b, Lamp1, Lamp2, and Atp6v0d1), cholesterol metabolism (Abdg5, Abcg8, Cyp7a1, and Hnf4a), and the oxidative stress response (Gstm2, Hmox1, and Hspb1) for targeted proteomics analysis