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When activated, these receptors trigger several beneficial effects: Enhanced insulin secretion in response to elevated blood glucose levels Suppression of glucagon release , reducing hepatic glucose production Delayed gastric emptying , which promotes satiety and reduces appetite Direct effects on appetite centres in the hypothalamus, leading to reduced food intake Commonly prescribed GLP-1 receptor agonists available in the UK include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon)

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[1] [7] Available under brand names including Ozempic, Wegovy, and Rybelsus, this medication mimics the action of endogenous GLP-1, a naturally occurring incretin hormone that plays a central role in glucose homeostasis and appetite regulation