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GLP-1R signaling in the brain exerts antidepressive effects by improving cognitive processes, promoting neuroprotection and neurotransmitter release Patients suffering from depression are characterized by impaired neuronal activity and synaptic plasticity dysfunction, resulting in volumetric changes in brain regions which regulate emotions or the stress response such as the hippocampus and the prefrontal cortex

This is not damage to taste budsit is a shift in how your brain processes food reward and flavor intensity