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In the early 21st century, the Danish company Novo Nordisk successfully developed Liraglutide, a peptide drug with 97% homology to human GLP-1

Seiwerth and colleagues (Inflammopharmacology, 1999) documented effects on angiogenic growth factor pathway signalling, and subsequent work has expanded characterisation to include VEGF receptor 2 upregulation, endothelial cell migration in capillary-formation assays, and improved healing in ischemia-reperfusion preparations

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