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Comparison Table 1

Semaglutide es un agonista del receptor de GLP-1 (pptido similar al glucagn tipo 1) aprobado por la FDA para el tratamiento de la diabetes tipo 2 (Ozempic, Rybelsus) y el control del peso (Wegovy)

Increased fat synthesis based on enhanced glycolytic activity (pklr1, sterol regulatory element-binding protein-1 [SREBP1c], fas, and liver X receptor a [lxra]) in aged mice partly accounted for hepatic steatosis (increased leukocytic infiltration) and necrosis (increased plasma aspartate aminotransferase [AST] activity), compared with reduced srebp1c and fas mRNA levels in young mice