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A reduced expression of Nrf2 has also been observed in human lens epithelial cells collected from donors of varying ages as well as diabetic patients

ACSL4 regulates the metabolism of arachidonic acid and eicosapentaenoic acid, contributing to the induction of ferroptosis and driving lipid peroxidation in the pathogenesis of various diseases [29, 30]

In a rat study, researchers noted that GHK administration prior to a maze test resulted in a reduction in apparent anxiety in the mice