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Despite high costs (the mean procedure cost amounts to PLN 5616) and the burden for the patient, LDL apheresis is still a very important complementary therapy for homozygous FH [259, 261263]

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The men with reduced sperm aneuploidy and improved sperm morphology as a result of the combination therapy in this study had significantly higher biochemical pregnancies, clinical pregnancies and live births after the treatment, despite having similar numbers of oocytes fertilized and embryos transferred [89]