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The molecule was rationally designed by Eli Lilly scientists to simultaneously engage three G-protein-coupled receptors central to metabolic homeostasis: the glucose-dependent insulinotropic polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor, and the glucagon receptor

However, it is currently investigational and not yet approved beyond trials

Impurities generated from asparagine at position 7 (Asn7) account for 62% of all degradation impurities and are the most critical factor affecting stability