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A well-designed 2010 randomized trial gave 41 men either 8 grams of citrulline malate or placebo before a lower-body resistance session
Besides diabetes and high blood pressure, the following additional health conditions may also contribute to CKD 1 : Cardiovascular disease Systemic or kidney infections Immune system conditions (eg, lupus) Inflammation of the glomeruli (tiny filters) in the kidneys Inherited kidney disease (eg, polycystic kidney disease) Congenital defects (eg, kidney malformation, urinary tract obstruction) Medications and toxins (eg, prolonged medication, chemical, or street drug exposure) Factors such as those described above and various others can contribute to the decline in kidney function characteristic of CKD
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Tolerability and side effects : Starting at a lower dose and increasing gradually helps minimize potential side effects
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