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In the Retatrutide trial, it was noted: this is an unusually high magnitude of efficacy as compared with findings in clinical trials of other anti- obesity agents, although it has been observed with bariatricmetabolic surgery . Basically, if we could give everyone in America bariatric surgery, we could probably solve the obesity epidemic

[DOI] [PMC free article] [PubMed] [Google Scholar] Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE, Reiss CW, Wang K, Iyer S, Dutta C, Clendaniel V, Amaonye M, Beach A, Berth K, Biswas S, Braun MC, Chen H-M, Colace TV, Ganey JD, Gangopadhyay SA, Garrity R, Kasiewicz LN, Lavoie J, Madsen JA, Matsumoto Y, Mazzola AM, Nasrullah YS, Nneji J, Ren H, Sanjeev A, Shay M, Stahley MR, Fan SHY, Tam YK, Gaudelli NM, Ciaramella G, Stolz LE, Malyala P, Cheng CJ, Rajeev KG, Rohde E, Bellinger AM, Kathiresan S, 2021

(visit source) Charlton KE, Rabinowitz TL, Geffen LN, Dhansay MA