Gutmans journey took a dramatic turn when a patient, a former Golden Gloves boxing champion named Howdy Meghdadi, burst into his office with a stack of research papers on glutathione, asking him to investigate its potential
If the peptide were made in the body, Szabo and his colleagues wrote, one would expect that over the course of decades, researchers would have identified the gene that encodes it, the cells that make it, the receptors that it interacts with, and the levels at which it occurs in the body
Lets break down what it actually does and why its worth paying attention to
421,422 Overexpression of GLUT-1 in the myocardium increased glucose levels in cardiomyocytes and revealed that FAO in the heart was inhibited and that a high fatty acid diet failed to upregulate FAO in these hearts, while glucose supply was significantly increased, further leading to activation of p38 mitogen-activated protein kinase and increased oxidative stress in the heart