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Arguably more impressive than the effect GLP-1RAs have on alcohol and nicotine use disorders is their impact on opioid cravings
Issue: No measurable vision improvement after 3 months Potential causes: Unrealistic expectations (expecting improvement vs slowed decline), advanced disease with minimal salvageable tissue, inadequate dosing or inconsistent use, wrong peptide for specific condition, peptides genuinely ineffective for individual, progression monitoring inadequate missing subtle benefits
Clinical chemistry 49, 17851796 (2003)
For companies that have historically focused on SBIR rather than STTR, Sims used the session to make a direct case for reconsidering that calculus given the new pathway
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