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Description

These medications have been shown to be beneficial in treating Type 2 diabetes, and several medications in this class have also been permitted for chronic weight management as well as cardiovascular risk reduction

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Hepatic glucagon increases gluconeogenesis and lipolysis via PKA/CREB activation, stimulates brown adipose tissue thermogenesis, and reduces hepatic triglyceride accumulation

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While the FDA has not yet approved Mounjaro for weight loss, a recommendation is expected by the end of this year

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