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It indicated that gene copy number has strongly correlated with the level of sod expression, not SOD activity

[DOI] [PubMed] [Google Scholar] 85.Malek F, Jiresova E, Dohnalova A, Koprivova H, Spacek R

Beyond lipid enzymes and microRNAs, exosomes derived from ferroptotic neurons also carry immunogenic DAMPs, which can be internalized by both microglia and astrocytes, triggering their innate immune recognition systems and initiating secondary immune responses

Importantly, oxidative stress and glutathione deficits have also been implicated in depression, bipolar disorder, and schizophreniabroadening their potential impact across mental health care