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The increased inflammatory response exacerbates kidney damage in CKD patients, showing how chronic stress contributes to the progression of kidney disease through gut-derived signals (Zhou T

Pearsons correlation coefficient was calculated to assess the strength of association between qRT-PCR and RNA-sequencing data

The cough helps clear mucus and any trapped material

These transgenic mice showed significantly reduced plasma testosterone levels (18% of normal)[124] and the IGF-I deficiency was correlated with an ultrastructural analysis of mutant Leydig cells revealing a significant developmental delay, with fewer and smaller Leydig cells than normal