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This imbalance occurs because the body senses too much thyroid hormone in the bloodstream, signaling the pituitary gland to reduce TSH release in an attempt to restore hormonal balance

Naveed Sattar, a professor of cardiometabolic medicine at the University of Glasgow who was not part of the team but was involved with previous work on the trial, said the findings are not a surprise, as excess weight is a well-established driver of elevated blood pressure and impaired glucose control

Intermittent fasting is not inherently dangerous with semaglutide, but it is often unnecessary because the medication already restricts intake naturally