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These have shown significant benefit not only for weight loss but have been shown to also improve many other comorbidities associated with obesity, including sleep apnea, cardiovascular disease, chronic kidney disease, and hepatic steatosis, said Dr

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Metabolites formed by hydroxylation reactions at the isocoumarin moiety of OTA (4-R/S- and 10-OH-OTA), and by the dechlorination of OTA leading to OTB, appear to represent minor detoxification pathways (EFSA 2020)

10.1016/j.nbd.2009.07.030 2 Alavi NainiS