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This differential responsiveness likely reflects the distinct metabolic and signaling environments that shape macrophage phenotypes within each tissue

Safety considerations also arise: Ashwagandha has occasionally precipitated thyrotoxicosis, and curcumin may interact with anticoagulants (41, 42, 235)

FASEB J 13 : 11691183 Pastore A, Massoud R, Motti C, Lo Russo A, Fucci G, Cortese C, Federici G 1998 Fully automated assay for total homocysteine, cysteine, cysteinylglycine, glutathione, cysteamine, and 2-mercaptopropionylglycine in plasma and urine