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This means that semaglutide could have benefits in terms of exercise capacity, Lalitha McSorley, physical therapist and owner of Brentwood Physiotherapy Calgary, tells Runners World

These effects commonly diminish once a state of microbial and metabolic equilibrium is reestablished in the GI tract (558)

Baseline assessment should establish B12 status (serum cobalamin, methylmalonic acid, homocysteine) and evaluate whether metabolic demands or absorption limitations suggest supplementation

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