Optimize intake of fruits and vegetables, citrus and cruciferous foods, sulfur-containing foods, herbs, spices, green tea, omega-3 fatty acids, fish, and lean protein sources
Additional risk factors include: Type 2 diabetes with impaired counter-regulatory responses long-standing diabetes may blunt the body's natural protective mechanisms against hypoglycaemia Renal impairment reduced kidney function can affect drug clearance and alter glucose homeostasis, particularly if on insulin or sulphonylureas Hepatic dysfunction the liver plays a central role in glucose production and metabolism Excessive caloric restriction very low-calorie diets combined with Wegovy may precipitate symptoms mimicking hypoglycaemia Increased physical activity particularly unplanned or intense exercise without adequate carbohydrate intake Alcohol consumption alcohol inhibits hepatic glucose production and can mask hypoglycaemia symptoms Elderly patients may have reduced awareness of hypoglycaemic symptoms and altered drug metabolism According to the Wegovy SmPC, patients with type 1 diabetes should not use Wegovy , as it is not licensed for this indication and the complex insulin requirements make management challenging
India is a very critical market, he added
More recently, Choi and colleagues evaluated the cost-effectiveness of SGLT2is and GLP-1RAs, taken individually, as first-line therapies for American patients with T2DM, compared with metformin as first-line therapy
