Glatter: In practice, many patients labeled non-responders to GLP-1 therapy are experiencing incomplete dosing, early discontinuation because of gastrointestinal side effects, insufficient treatment duration, or competing metabolic drivers such as severe insulin resistance, sleep disruption, sarcopenia, or medication-associated weight gain
Diffusion-weighted imaging can distinguish acute lacunar infarction from chronic lesions
grip strength, activities of daily living score, SF-36, sit to stand) merit further study as well
Referral pathways typically include general surgery consultation for symptomatic gallstones or cholecystitis, while suspected bile duct stones (choledocholithiasis) or cholangitis may require gastroenterology evaluation for possible endoscopic retrograde cholangiopancreatography (ERCP)