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It also reduces HbA1c within three months and maintains it thereafter in the diabetic population overall

Nitric oxide prodrugs Nitric oxide (NO) is involved in several key physiological and pathological processes 122

Abbreviations SGLT-2i: Sodium-dependent glucose transporters 2 inhibitors GLP-1 Ras: Glucagon-like peptide 1 COVTs: Cardiovascular outcomes trials MACE: Major adverse cardiovascular events HHF: Hospitalization for heart failure CV death: Cardiovascular death HHF or CV death: Hospitalization for heart failure or cardiovascular death MI: Myocardial infarction T2DM: Type 2 diabetes mellitus RoB 2: Risk-of-bias tool CIs: Confidence intervals HRs: Hazard ratios References Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB, Stein C, Basit A, Chan JCN, Mbanya JC, et al