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This cellular damage contributes to clinical sequelae such as prolonged mechanical ventilation dependence and surfactant deficiency ( Apnea of prematurity represents another frequent challenge in this vulnerable population

In animals and humans, circulating leptin levels are directly related to the amount and size of adipocytes, and so better correspond with total fat mass than with bodyweight

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A similar loop-mediated mechanism was also observed in CoAPR, where the pantothenate arm of a tightly bound coenzyme A molecule swings between two active sites of the enzyme 17