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Description

159 SIRT1 alleviates ER stress by deacetylating molecules such as eIF2 and CHOP, 32 inhibiting excessive activation of the unfolded protein response, 160 and reducing expression of stress-related proteins including GRP78 and ATF4

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That's not a dismissal

Martin Chandler and Ian David Boardley of the University of Birminghams School of Sport, Exercise & Rehabilitation Sciences wrote in a paper last year that there is limited research available on the health impacts of such drugs in sports

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